Neurological complications of Covid-19: Narrative review (ir↗)

Complicações neurológicas da Covid-19: revisão narrativa

Autors : Mateus Marinho Silva de Souza, Matheus Araújo de Oliveira Farias, Ana Rita de Oliveira Souza da Silva, Nataly Regina Fonseca Carvalho de Medeiros, Marcelo Moraes Valença

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Abstract:

The pandemic caused by the new coronavirus has brought great challenges to science, given its high transmission rate, which generates a crisis in the health and economic systems around the world and requires rapid responses from researchers. We know that the receptor for angiotensin-converting enzyme 2 plays an important role in infection. This receptor is also present in neurons and glial cells of the motor cortex, posterior portion of the cingulate gyrus, ventricles, substantia nigra, olfactory bulb, middle temporal gyrus, solitary tract nucleus, ventrolateral medulla and dorsal nucleus of the vagus. Which is why the neuroinvasion mechanism needs to be better understood. Its neurological manifestations can often present as mild symptoms, such as hyposmia and ageusia. From a literature review, in this article, we investigated the neurological repercussions of virus infection, in which the consequences of Covid-19 on the central nervous system, the inflammatory response caused by its presence and the state of hypercoagulability were studied, as well as the way complications, are triggered, from headache to encephalopathy or stroke.